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Schematics, Diagrams, Circuits, and Given Data: ia = 1 mA; ib = 2 mA; R1 = 1 k ;

s2 )

Analysis: To write the node equations, we start by selecting the reference node (step 1)

Lubricant may impose limitations Self-contained assemblies can be used with Excellent with certain limits of Auxiliary high self-contained pressure is load, speed, grease or oil and diameter; necessary lubricant beyond this, oil circulation is necessary Excellent Good

0.15 (0.15

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Figure 37 illustrates that two nodes remain after the selection of the reference node Let us label these a and b and de ne voltages va and vb (step 2)

0.4)

Next, we apply KCL at each of the nodes, a and b (step 3): ia va va vb =0 R1 R2 (node a) (node b)

Substituting the numerical values in these equations, we get 3 10 3 va 2 10 3 vb = 1 10 3 2 10 3 va + 267 10 3 vb = 2 10 3 or 3va 2vb = 1 2va + 267vb = 2 The solution va = 1667 V, vb = 2 V may then be obtained by solving the system of equations

The McGraw Hill Companies, 2001

(Contd )

Solve the circuit equations obtained in Example 32 using Cramer s rule (see Appendix A)

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P R O B L E M S *

Known Quantities: Linear system of equations Find: Node voltages Analysis: The system of equations generated in Example 32 may also be solved by using

linear algebra methods, by recognizing that the system of equations can be written as: 3 2 2 267 va vb = 1V 2V

conglomerate population. If the migration rate was 0.1, calculate the frequency of t in the original, native population.

By using Cramer s rule (see Appendix A), the solution for the two unknown variables, va and vb , can be written as follows: va = 1 2 3 2 3 2 3 2 2 267 2 267 1 2 2 267 = 667 (1)(267) ( 2)(2) = = 1667 V (3)(267) ( 2)( 2) 4

Table 710 (Contd)

8 (3)(2) ( 2)(1) = =2V (3)(267) ( 2)( 2) 4

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1. Consider a locus with alleles A and a in a large, randomly mating population under the in uence of mutation. a. If the mutation rate of A to a is 6 10 5, and the back-mutation rate to A is 7 10 7, what is the equilibrium frequency of a b. If q 0.9 in generation n, what would it be one generation later, under only the in uence of mutation 2. Derive an expression for mutation equilibrium when no back mutation is occurring. 3. Consider a population in which p 0.9 and q 0.1. If the forward mutation rate, A a, is 5 10 5 and the reverse mutation rate, a A, is 2 10 5, calcu^ late the equilibrium frequency, q , of the a allele. 4. If the forward mutation rate, A a, is ve times the reverse mutation rate, what is the equilibrium frequency of the a allele

Comments: While Cramer s rule is an ef cient solution method for simple circuits (eg, two nodes), it is customary to use computer-aided methods for larger circuits Once the nodal equations have been set in the general form presented in equation 39, a variety of computer aids may be employed to compute the solution You will nd the solution to the same example computed using MathCad in the electronic les that accompany this book

10. In a population of ve hundred individuals with a frequency of allele A of 0.7, what is the ultimate fate of the A allele What is the probability that the population will eventually lose the A allele How many are N/5 generations 4N generations

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