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Differentiate from other skin conditions involving the same areas, such as interdigital erythrasma (use Wood s light) Psoriasis may be a cause of chronic scaling on the palms or soles and may cause nail changes Repeated fungal cultures should be negative, and the condition will not respond to antifungal therapy Contact dermatitis (from shoes) will often involve the dorsal surfaces and will respond to topical or systemic corticosteroids Vesicular lesions should be differentiated from pompholyx (dyshidrosis) and scabies by proper scraping of the roofs of individual vesicles Rarely, gramnegative organisms may cause toe web infections in the setting of prior tinea or in its absence Culture is not very specific, because gram-negative organisms can be cultured from normal toe webs This entity is treated with aluminum salts (see below) and imidazole antifungal agents or ciclopirox

4 Tinea Versicolor (Pityriasis Versicolor)

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The C# language is disarmingly simple, which makes it good for beginners, but C# also includes all the support for the structured, component-based, object-oriented programming that one expects of a modern language built on the shoulders of C++ and Java In other words, it s a fully featured language appropriate for developing large-scale applications, but at the same time it is designed to be easy to learn A small team led by two distinguished Microsoft engineers, Anders Hejlsberg and Scott Wiltamuth, developed the original C# language Hejlsberg is also known for creating Turbo Pascal, a popular language for PC programming, and for leading the team that designed Borland Delphi, one of the first successful integrated development environments (IDEs) for client/server programming The goal of C# is to provide a simple, safe, object-oriented, high-performance language for NET development C# is simple because there are relatively few keywords.

The most important complication is suicide, which often includes some elements of aggression Suicide rates in the general population vary from 9 per 100,000 in Spain to 20 per 100,000 in the United States to 58 per 100,000 in Hungary In individuals with depression, the lifetime risk rises to 10 15% Men tend toward successful suicide, particularly in older age groups, whereas women make more attempts with lower mortality rates An increased suicide rate is being observed in the younger population, ages 15 35 Patients with cancer, respiratory illnesses, AIDS, and those being maintained on hemodialysis have higher suicide rates Alcohol is a significant factor in many suicide attempts There are four major groups of people who make suicide attempts By far the greatest number fall into the category of situational problems (the despair of ordinary people) There is often great ambivalence they don t really want to die, but they don t want to go on as before either A suicide attempt in such cases may be an impulsive or aggressive act not associated with significant depression In other cases a suicide attempt is clearly a stratagem for controlling or hurting others The high-risk groups are those with severe depressions or psychotic illnesses Severe depression may be due to exogenous conditions (eg, AIDS, whose victims have a suicide rate over 30 times that of the general population) or endogenous conditions (eg, panic disorders) This group also includes those who may not be diagnosed as having depression but who are overwhelmed by a stressful situation often with an aspect of public humiliation (eg, the man charged with child molestation who hangs himself in his cell) Anxiety, panic, and fear are major findings in suicidal behavior A patient may seem to make a dramatic improvement, but the lifting of depression may be due to the patient s decision to commit suicide Those with psychotic illness tend not to verbalize their concerns, are unpredictable, and are often successful but make up only a small percentage of the total Suicide is ten times more prevalent in patients with schizophrenia than in the general population, and jumping from bridges is a more common means of attempted suicide by schizophrenics than by others In one study of 100 jumpers, 47% had schizophrenia.

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