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The mouse pointer s failure to move across the screen indicates that the computer cannot communicate properly with the mouse, so it is not receiving the appropriate signals to move the mouse pointer One reason for this problem could be an IRQ conflict with another device Because a serial mouse must use a COM port, it also uses that port s IRQ and I/O address However, recall that some COM ports can share IRQ addresses If another device attached to a COM port shares an IRQ with the mouse COM port, the mouse will probably not work at all If you are running Microsoft Windows 9X you would use the Device Manager which is located under the Control Panel to determine if there is a resource conflict If there is, move the offending device to a different COM port Windows 2000 and Windows XP use Device Manager which resides in Computer Management, which is accessible under the Control Panel If the problem is not IRQ related, it might be driver related That is, the mouse driver might be either corrupted or missing altogether If you suspect a missing driver, you need to manually load the driver from the Setup disk that came with the mouse If there is no driver disk, try simply restarting the computer Most mice are Plug and Play, so the OS might automatically detect your mouse and load the appropriate driver for it at startup If you suspect that a mouse driver exists but has become corrupted, use the Device Manager or the Mouse icon in the Control Panel to remove the existing driver and reload the driver Finally, an unresponsive mouse might be a symptom of a malfunctioning adapter card if it is a bus mouse A bus mouse adapter card must be installed and configured in the same manner as other expansion cards Ensure that it has the proper resources and that there are no conflicts Next, ensure that the adapter card s device driver is loaded You can also try opening the computer to ensure that the card is properly seated in the expansion slot or try replacing the card Most newer systems provide a dedicated connection for the mouse and generally do not use a COM port for mouse connections A USB mouse would be a better choice than a serial mouse if the mouse port physically failed for some reason You would want to attempt to verify that the port has in fact failed by trying another mouse and reinstalling the driver.

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prickling and pain Paresthesias arising from ectopic discharges in large sensory bers can be induced by nerve compression, hypocalcemia, and diverse diseases of nerves Band-like sensations are the result of dysfunction in large sensory bers, either in the periphery or their continuation in the posterior columns Also, certain sensory symptoms suggest an anatomical location of nerve disease; for example, lancinating pains that radiate to the back or neck implicate root or, less often, sensory ganglion disease The presence of persistent paresthesias should always raise the suspicion of a lesion involving sensory pathways in nerves, spinal cord, or higher structures Most often, the large bers in the peripheral nerves or posterior columns are implicated Evanescent paresthesias, of course, may be of no signi cance Every person has had the experience of resting a limb on the ulnar, sciatic, or peroneal nerve and having the extremity fall asleep This is due to compressive interruption of axonal transport and not to ischemia of the nerves or other components of the limb, as is commonly assumed The hyperventilation of anxiety may cause paresthesias of the lips and hands (sometimes unilateral) from diminution of CO2 and thereby of ionized calcium; tetany may also occur, with carpopedal spasms However, these sensory experiences are transient and should not be confused with the persistent, albeit frequently uctuating, paresthesias of structural disease of the nervous system Severe acral and peripheral paresthesias with perversion of hot and cold sensations are characteristic of certain neurotoxic shell sh poisonings (ciguatera) Also worth comment are vibratory paresthesias, which we have encountered in only a handful of patients One articulate physician described the sensation as a high-amplitude, low-frequency buzz that was distinctly different from the more common prickling paresthesias, burning, numbness, etc We have the impression that these sensations are almost always a manifestation of central sensory disease, in one case probably attributable to the posterior columns and in another to cerebral disease Beyond this, little is known about this symptom Effect of Age on Sensory Function A matter of importance in the testing of sensation is the progressive impairment of sensory perception that occurs with advancing age This requires that sensory thresholds, particularly in the feet and legs, always be assessed in relation to age standards The effect of aging is most evident in relation to vibratory sense, but proprioception, as well as the perception of touch, and fast pain are also diminished with age Sweating and vasomotor re exes are reduced as well These changes, which are discussed further in Chap 29, are probably due to neuTable 9-1 Origin of aberrant sensations.

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