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The S-alkylcysteine sulphoxides which are found in members of the onion or Allium genus and are discussed later in this chapter in the section on garlic The cruciferous plants include cabbage, broccoli, brussels sprouts, cauli ower, swede, turnip, mustard, radish, watercress, rocket, horseradish and rape, and these all produce glucosinolates Breakdown products of glucosinolates called isothiocyanates which are released when the plant is damaged by processing or chewing are responsible for the hot and bitter avours associated with foods such as mustard and horseradish The seeds of ordinary varieties of rape have a bitter taste owing to the presence of a glucosinolate, but genetically modi ed varieties have been produced in which this compound does not accumulate, making it more palatable, for example as an animal feed A number of in vitro studies have shown that certain isothiocyanates derived from dietary brassica have potential anti-cancer properties.

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There is also some epidemiological evidence that high consumption of brassica vegetables is associated with a low risk of lung and colorectal cancer (see Johnson 2003 for more details and references) How might these secondary metabolites reduce risk of chronic disease Jackson (2003) has reviewed the potential mechanisms by which bioactive substances, including plant secondary metabolites, may act to reduce the risk of chronic degenerative diseases such as cancer and heart disease Some of the potential sites of action of plant secondary metabolites and other bioactive substances that Jackson (2003) discusses are listed below Some potential environmental carcinogens are activated and made more damaging to DNA and other cellular components by the initial stages in the body s detoxi cation processes So-called phase I enzymes convert environmental chemicals into more water-soluble metabolites to facilitate their excretion This may amount to a metabolic activation of some potential carcinogens.

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In simple applications, transactions may perform actions against a single database, a single table, or some combination of the two. Simple applications may fall at the low end of the spectrum of the types of applications that are written today; at the other end of the spectrum are complex applications. Transactions in complex applications can touch multiple databases that can be on the same network or scattered across a WAN. This means that transaction managers and DBMSes must be highly coordinated in order to ensure that transactions that span multiple databases adhere to the transaction requirements described earlier.

radar interferometry (InSAR) and GIS so that CGPS can monitor small-scale deformation:

It has been suggested that certain isothiocyanates derived from dietary glucosinolates (eg from brassica vegetables) may inhibit this metabolic activation of potential carcinogens The second stage in the detoxi cation of foreign chemicals involves their conversion by so-called phase II enzymes to harmless metabolites Some plant chemicals may induce the formation of phase II enzymes and so accelerate the detoxi cation process The sulphur-containing compounds found in the Allium (onion) genus, as well as some isothiocyanates, may have such an effect This has led to suggestions that garlic and broccoli, for example, may have anti-cancer properties High doses of compounds exerting this effect may also increase the rate of metabolism of some prescription drugs and thus render them less effective, for example Hypericum (St John s wort) extracts are believed to interfere with the actions of several prescription drugs in this way.

8 30.1

Certain carcinogens may interact with DNA to cause alteration of bases such as guanine and cytosine, for example by the addition of hydroxyl or alkyl groups If these changes are not repaired by the cells DNA repair mechanisms, they can ultimately lead to potentially carcinogenic mutations Many plant substances with antioxidant activity such as the antioxidant vitamins, carotenoids and many avonoids may reduce this DNA damage..

Receipt of Federal SSI (Supplemental Security Income)b 1563 (352) 1917 (618) 1587 (352) 1929 (687)

face-to-face interactions and lie slightly more via a more distant modality (eg, the telephone) (DePaulo, Kashy et al, 1996; Vrij, Ennis et al, 2006) We further found that when lying, compared to when telling the truth, participants experienced more cognitive load, tried harder to appear credible, and could embrace less what they had said (Vrij, Ennis, et al, 2006) Despite the support for Zuckerman et al s and DePaulo s perspectives, it is important to note that those diary studies revealed that the majority of lies were not really taxing Participants in DePaulo, Kashy et al s (1996) diary study indicated that their lies were generally not serious, that they put little effort into planning them, and that they did not worry much about the possibility of being caught.

Inline formatting elements include the following: Bold (<b>) Italic (<i>) Big text (<big>) Small text (<small>) Emphasized text (<em>) Strong text (<strong>) Teletype (monospaced) text (<tt>) For example, consider the following sample paragraph, whose output is shown in Figure 2-9.

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