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28 Xu, Z Q; Buckheit, R W; Jr; Stup, T L; Flavin, M T; Khilevich, A; Rizzo, J D; Lin, L; Zembower, D E In vitro anti-human immunode ciency virus (HIV) activity of the chromanone derivative, 12-oxocalanolide A A novel NNRTI Bioorg Med Chem Lett, 1998, 8: 2179 2184 29 Buchheit, R W; Jr; Russell, J D; Xu, Z Q; Flavin, M Anti-HIV-1 activity of calanolides used in combination with other mechanistically diverse inhibitors of HIV-1 replication Antiviral Chem Chemother, 2000, 11: 321 327 30 Buchheit, R W; Jr; White, E L; Eliakas-Boltz, V; Russell, J; Stup, T L; Kinjerski, T L; Osterling, M C; Weigand, A; Bader, J P Unique anti-human immunode ciency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide Antimicrob.

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Agents Chemother, 1999, 43: 1827 1834 31 Xu, Z Q; Lin, Y M; Flavin, M T US Patent Application No 09/417,672/1999; US Patent 6,268,393 B1, 2001 32 Xu, Z Q; Hollingshead, M G; Borgel, S; Elder, C; Khilevich, A; Flavin, M T In vivo anti-HIV activity of ( )-calanolide A in the hollow ber mouse model Bioorg Med Chem Lett, 1999, 9: 133 138 33 Pengsuparp, T; Serit, M; Hughes, S H; Soejarto, D D; Pezzuto, J M Speci c inhibition of human immunode ciency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of Calophyllum teysmannii J Nat Prod, 1996, 59: 839 842 34 Shi, X W; Attygalle, A B; Liwo, A; Hao, M H; Meinwald, J Absolute stereochemistry of Soulattrolide and its analogues.

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const S& sampleAccumulator, const Handle<PP>& cvPathPricer = Handle<PP>(), result_type cvOptionValue = result_type()); void addSamples(Size samples); const S& sampleAccumulator(void) const; private: Handle<PG> pathGenerator_; // path generator Handle<PP> pathPricer_; // path pricer S sampleAccumulator_; // sample accumulator Handle<PP> cvPathPricer_; // control variate path price result_type cvOptionValue_; // control variate option value bool isControlVariate_; }; // inline de nitions template<class S, class PG, class PP> inline MonteCarloModel<S, PG, PP>::MonteCarloModel( const Handle<PG>& pathGenerator, const Handle<PP>& pathPricer, const S& sampleAccumulator, const Handle<PP>& cvPathPricer, MonteCarloModel<S, PG, PP>::result_type cvOptionValue : pathGenerator_(pathGenerator), pathPricer_(pathPricer), sampleAccumulator_(sampleAccumulator), cvPathPricer_(cvPathPricer), cvOptionValue_(cvOptionValue) { if (cvPathPricer_.isNull()) isControlVariate_= false; // no control variates else isControlVariate_= true; // use control variates } template<class S, class PG, class PP> inline void MonteCarloModel<S, PG, PP>::addSamples(Size samples) { for(Size j = 1; j <= samples; j++) { sample_type path = pathGenerator_->next(); result_type price = (*pathPricer_)(path.value); if (isControlVariate_) price += cvOptionValue_-(*cvPathPricer_)(path.value); sampleAccumulator_.add(price, path.weight); } } template<class S, class PG, class PP> inline const S& MonteCarloModel<S, PG, PP>::sampleAccumulator() const { return sampleAccumulator_; }

J Org Chem, 1998, 63: 1233 1238 35 Dharmaratne, H R W; Wanigasekera, W M A P; Mata-Greenwood, E; Pezzuto, J M Inhibition of human immunode ciency virus type 1 reverse transcriptase activity by cordatolides isolated from Calophyllum cordato-oblongum Planta Med, 1998, 64: 460 461 36 Creagh, T; Ruckle, J L; Tolbert, D T; Giltner, J; Eiznhamer, D A; Dutt, B; Flavin, M T; Xu, Z Q Safety and pharmacokinetics of single doses of ( )-calanolide, A: A novel, naturally occurring nonnucleoside reverse transcriptase inhibitor, in health, human immunode ciency virus-negative human subjects Antimicrob Agents Chemother, 2001, 45: 1379 1386 37 Currens, M J; Gulakowski, R J; Mariner, J M; Moran, R A; Buckheit, R W; Jr; Gustafson, K R; McMahon, J B; Boyd, M R.

Aside from those two projects, most of the other Linux Toys II projects can be done with smaller bits of extra hardware. For the X10 projects, you need hardware to connect your PC to your location s power source to send X10 signals (usually from the PC s serial port). Then you can add as many X10 hardware modules around your place as you like. For the bootable pen drive project, you need to pick a pen drive (1GB pen drives are now available for just over $50). The topics of interest covered in Linux Toys II projects that I ve just described here are just the tip of the iceberg of what you can do with Linux and open source software. But the skills you learn in building these projects will scale down to handheld devices or up to enterprise computing clusters.

Large apertures let lots of light into the camera to form the image on your sensor. They also provide the shallowest depth of eld, which when used creatively blurs the background or foreground and places all the emphasis on your subject. Lenses that have maximum apertures of f/2.8 and larger are often called fast glass for their ability to allow you to shoot at faster shutter speeds because they let so much light into the camera.

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