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Archival examination of the Hawthorne experiments indicates a rather different history: These objective experiments actually entailed prior knowledge of the effects of varying workplace conditions, suppression of problematic and contradictory.

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had over 2,800 members and a number of formal interest groups, including those on women s health, minority health, education and training, and international affairs International Organizational Efforts Health psychology was also becoming more organized in Europe during the same period of time Six years after APA Division 38 was founded, Professor Stan Maes organized an international conference on health psychology in Tilburg (the Netherlands), which then initiated the formation in 1986 of the European Health Psychology Society (EHPS) (Schwarzer & Johnston, 1994) At this meeting were also Marie Johnston (UK), John Weinman (UK), Ralf Schwarzer (Germany), Ad Kaptein (the Netherlands), Lothar Schmidt and Peter Schwenkmezger (Germany), and Jan Vinck (Belgium), who became key people in the development of health psychology in Europe and in their own countries.

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It is interesting to note that among the 60 participants was a large contingent from the United States, including Charles Spielberger and Irwin Sarason, who supported the development of a European association At that conference, it also became apparent that a substantial amount of research was being conducted in various European countries on topics relevant to health psychology (Maes, 1990; Maes, Spielberger, Defares, & Sarason, 1988) The creation of the EHPS in 1986 represents an important landmark for the development of health psychology in Europe The purpose of the EHPS is the promotion and development within Europe of empirical and theoretical research and applications of health psychology and the interchange of information relating to this subject between European members and other associations throughout the world (Schwarzer & Johnston, 1994, p 4).

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et al., 2001; Liu et al., 1999], and for clinical applications there is a risk that oncogenic factors could be transmitted to the patient. Thus the use of primary hepatocyte-based systems would eliminate these de ciencies, providing the appropriate collection of liver functions. The development of primary hepatocyte-based approaches is the focus of substantial ongoing research, yet progress has been hampered by the loss of liver-speci c functions exhibited by isolated hepatocytes in vitro. Furthermore, particularly for human hepatocytes, despite the signi cant proliferative capacity during regenerative responses in vivo, mature hepatocyte proliferation in culture is limited. As a result, alternative primary cell sources for liver cell-based therapies are also being investigated [Allen and Bhatia, 2002], such as various stem cell populations (embryonic and adult), which retain signi cant proliferative ability in vitro and exhibit pluripotency (embryonic) or multipotency (adult), thereby providing a potential source of hepatocytes as well as other liver cell types. This prospective capacity to generate concurrently additional liver cell types, for example, bile duct epithelial cells from a single proliferative precursor, represents a potential means for enhancing liver-speci c function of a tissueengineered construct. However, this process may require complex differentiation cues, and many challenges remain, including the ability to control the microenvironment and organize resultant structures, strategies for delivery, etc., before stem cells can be utilized as sources of large numbers of hepatocytes or other liver cell types, particularly within multicellular systems. In addition, regardless of the cell source, the stabilization of hepatocyte functions remains a fundamental issue.

Since then, the EHPS annual conferences have offered an important setting for exchange among the major European scholars in the eld They also provide a forum for the discussion of issues facing health psychology in Europe, both as a science and a profession The growing number of participants in the EHPS conferences from 1988 to 1996 illustrates the development of the eld There were 60 participants in 1986, 100 in 1989 (Utrecht, the Netherlands), and 500 in 1996 (Dublin, Ireland) Another important landmark in the de nition of health psychology in Europe was a document written by the European Federation of Professional Psychologist s Associations (EFPPA) and published by the WHO Regional Of ce for Europe in 1984; this document clari es the contribution of psychology to the health eld The EFPPA has played an important role in the development of professional health psychology, as will be detailed later..

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how to write pdf file in asp.net c#

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