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humidity data corroborated experimental ndings regarding the effect of the variables studied on tablet stability [180] It is known that hard gelatin capsule brittleness is a function of moisture content A study has been carried out to indicate that the brittleness of empty capsules occurred at humidities below 40% Mexitil-loaded capsules exhibited a similar pro le The SDMT model was employed to estimate the nal relative humidity for the Mexitil/gelatin capsule system and results were presented to demonstrate the general applicability of the SDMT model for predicting the incidence of brittleness problems and for the formulation to ensure the absence of brittleness [181] The sorption of two weak acids (warfarin and thiopentone) and two weak bases (chlorpromazine and diltiazem) into PVC infusion bags was described by a constant partition model.

backward a small distance F P by pushing the mirror support against a metallic bar F P, xed with respect to lens L Interferograms obtained with lenses having third order aberrations will be shown in Section 27 Testing a large lens on the Twyman Green interferometer requires the use of a beam-splitter plate even larger than the lens To avoid this dif culty, according to Burch (1940), Williams suggested later by Hopkins (1962) for use with a gas laser in an unequal path con guration Complete small telescopes can also de tested with good results as shown by Ostrovskaya and Filimonova (1969) 243 Testing of Microscope Objectives Twyman (1920, 1923) also used his instrument for the testing of microscope objectives with good success.

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8.3.2 Design Criteria The ve design criteria for the implementation of digital communication networks for PACS are speed, standardization, fault tolerance, security, and component cost. 8.3.2.1 Speed of Transmission Table 8.4 shows that the standard Ethernet is adequate between imaging devices and acquisition gateway computers. For image transfer from the acquisition gateway computers to the image archive servers, fast Ethernet or ATM should be used if the acquisition computer supports the technology. For image transfer between the PACS Server to WSs, ATM, fast, or gigabit Ethernet should be used. 8.3.2.2 Standardization The throughput performance for each of the two networks described above (Ethernet and ATM) can be tuned through the judicious choice of software and operating system parameters. For example, enlarging the TCP send and receive buffer within the UNIX kernel for Ethernet and ATM network circuits can increase the throughput of networks using TCP/IPs. Alternatively, increasing the memory data buffer size in the application program may enhance transmission speed. The altering of standard network protocols to increase network throughput between a client-server pair can be very effective. The same strategy may prove disastrous in a large communication network, however, because it interferes with network standardization, making it dif cult to maintain and service the network. All network circuits should use standard TCP/IP network protocols with a standard buffer size (e.g., 8192 bytes). Still some manufacturers use dedicated or proprietary transmission protocols within their own PACS components to achieve higher speed. Once they are connected, any components not from the same vendor even with standard transmission protocols would render these components inoperable within this vendor s network environment. 8.3.2.3 Fault Tolerance Communication networks in the PACS infrastructure should have backup. All active ber-optic cables, twist pairs, Ethernet backbone (thicknet and twisted pair), and switches should have spares. Because standard

The arrangement is essentially the one used for a lens, but a convex mirror, in general, cannot be employed because of the short focus of the objective Since the microscope sometimes works at a nite tube length, a negative lens is added to change the collimated light and simulate a light source 16 cm away This lens must be corrected for spherical aberration, but it is not necessary to correct it quasi-monochromatic As shown in Figure 227, several arrangements can be used to test an objective, the most common being a spherical concave mirror with its center of curvature at the focus of the objective A solid spherical re ector slightly thicker than a hemisphere can serve to simulate the presence of a cover glass A plane mirror at the focus of the objective can also be used, but in this case the wavefront is rotated 180 .

PVC water partition coef cients were obtained using three different methods: equilibrium values for sorption into PVC bags, the sorption versus pH relationship, and partition into PVC strips The data were compared with similar values derived from a liquid liquid partition system and different organic solvents (octanol, dichloromethane, carbon tetrachloride, and hexane) Octanol is the preferred solvent, and it is suggested that octanol water partition data can be used to predict sorption behavior [182] Reports have shown that changes in the hardness of tablets composed of lactose and cornstarch were due to variation of the moisture content.

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